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Exploring the clinical efficacy and mechanism of iTBS combined with stellate ganglion block in treating CRPS I after stroke based on multimodal assessment

Exploring the clinical efficacy and mechanism of iTBS combined with stellate ganglion block in treating CRPS I after stroke based on multimodal assessment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122730
Enrollment
Unknown
Registered
2026-04-16
Start date
2026-04-16
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with type I CPRS after stroke

Interventions

Experimental group:Applying stellate ganglion block combined with iTBS on the basis of the control group

Sponsors

Shandong Provincial Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.The diagnosis complies with the "Stroke Diagnosis Criteria" in the "Chinese Guidelines and Consensus for the Diagnosis and Treatment of Cerebrovascular Diseases (2016 Edition)", and the lesion site has been confirmed by cranial CT or MRI; 2.The age is between 18 and 70 years old; 3.The affected side of the upper limb experiences pain, and it conforms to the newly revised Budapest (Budapest) criteria in 2010; 4.Other drug treatments have not been effective; 5.The patient consents voluntarily, the family is informed, and the informed consent form is signed.

Exclusion criteria

Exclusion criteria: 1.Those who already have diseases such as peripheral nerve damage, shoulder arthritis, rotator cuff injury, shoulder joint fractures, and rheumatoid arthritis that affect the upper limb's movement function before the stroke; 2.Patients with unstable conditions or those with severe physical diseases; ? Those with cognitive dysfunction; 3.Those with cognitive dysfunction; 4.Those currently taking drugs for neuropathic pain treatment; 5.Those with intracranial metal foreign bodies or with implanted cardiac pacemakers, heart stents, cochlear implants, increased intracranial pressure, having had epileptic seizures or a family history of epilepsy; 6.Those with severe mental disorders or other reasons that prevent cooperation.

Design outcomes

Primary

MeasureTime frame
Simplified McGill Pain Questionnaire;

Secondary

MeasureTime frame
Functional Magnetic Resonance Imaging;Fugl-Meyer assessment scale;Motor Function Status Scal;Improved Barthel Index;Blood factors;

Countries

China

Contacts

Public ContactBo Zhihui

Shandong Provincial Third Hospital

15666630727@163.com+86 531 8165 6661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026