Burn
Conditions
Interventions
Oliceridine group:Postoperatively, oliceridine was prepared in a patient-controlled analgesia (PCA) pump for postoperative analgesia.
Sufentanil group:Postoperatively, an equivalent dose of sufentanil was prepared in a patient-controlled analgesia (PCA) pump for postoperative analgesia.
Sponsors
Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–65 years; 2. Patients undergoing escharotomy and skin grafting under general anesthesia; 3. American Society of Anesthesiologists (ASA) physical status I or II, with a burn area of 10%–30% total body surface area (TBSA); 4. Informed consent obtained from the patient or legal guardian; 5. Patients are conscious and able to cooperate with the study procedures; 6. Body mass index (BMI) between 18.5 and 35.0 kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Allergy or contraindication to anesthetics or antiemetics used in the study; 2. Comorbid cognitive dysfunction; 3. Presence of pain caused by other conditions; 4. Comorbid chronic pulmonary disease or bronchial asthma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions within 48 hours postoperatively;Age;15-item quality of recovery;Body Mass Index;America Society of Anesthesiologist; | — |
Countries
China
Contacts
Public ContactFan Yuan;Liu Xinfeng
Affiliated Hospital of Zunyi Medical University
Outcome results
None listed