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Remimazolam Combined with Low-Dose Propofol for Sedation in Adult Patients Undergoing Endoscopic Ultrasonography

Remimazolam Combined with Low-Dose Propofol for Sedation in Adult Patients Undergoing Endoscopic Ultrasonography

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122722
Enrollment
Unknown
Registered
2026-04-16
Start date
2026-04-16
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early gastrointestinal cancer and elevated lesions

Interventions

Group P:Receive 1.5 - 2 mg/kg of propofol for anesthesia induction
Group R:Receive 0.3 mg/kg of tropisetron hydrochloride for anesthesia induction
Group PR:Received 1mg/kg propofol + 0.2mg/kg remifentanil for anesthesia induction

Sponsors

Mianyang 404 Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and less than 65 years old, gender not restricted; 2. ASA score is level I or II; 3. BMI between 18 kg/m^2 and 30 kg/m^2; 4. Clearly understand and voluntarily participate in this study, and sign the informed consent form by oneself.

Exclusion criteria

Exclusion criteria: 1. Including severe liver or kidney dysfunction, cardiovascular diseases (such as acute or decompensated heart failure, acute coronary syndrome, third-degree atrioventricular block or severe heart valve disease); 2. Brain diseases, mental disorders; 3. Allergy to the drugs involved in this study (such as benzodiazepines, propofol, opioids, flumazenil or naloxone); patients judged to have difficulty in airway management or those who refuse to participate in this study for any reason; 4. Patients with contraindications for EUS; 5. Pregnant women; 6. Patients planning to undergo therapeutic EUS surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of low SPO2;

Secondary

MeasureTime frame
Anesthesia induction time;Anesthesia recovery time;Time from discontinuation of anesthetic agents to an Aldrete Score = 9;

Countries

China

Contacts

Public ContactWen Xu

Mianyang 404 Hospital

18281969096@163.com+86 182 8196 9096

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026