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A study on the correlation between ABCG1 gene promoter methylation and type 2 diabetic kidney disease

A study on the correlation between ABCG1 gene promoter methylation and type 2 diabetic kidney disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122709
Enrollment
Unknown
Registered
2026-04-16
Start date
2025-06-05
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetic kidney disease

Interventions

Sponsors

The Affiliated Hospital of Inner Mongolia Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
42 Years to 69 Years

Inclusion criteria

Inclusion criteria: 1. Diabetic Kidney Disease Group: All patients had type 2 diabetes mellitus and met the diagnostic criteria for diabetic nephropathy as specified in the 2017 Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes Mellitus; aged over 18 years. 2. Type 2 Diabetes Mellitus Group: Met the diagnostic criteria for type 2 diabetes mellitus as specified in the 2017 Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes Mellitus.

Exclusion criteria

Exclusion criteria: Patients with primary glomerulonephritis, primary nephrotic syndrome, congenital polycystic kidney disease, and other secondary renal diseases such as lupus nephritis, purpura nephritis, and hypertensive nephropathy were excluded. Also excluded were those with renal cell carcinoma, pyelocarcinoma, embryonal tumors, and those who had undergone renal surgery within the past 6 months. In the control group, individuals with underlying diseases including hypertension, diabetes mellitus, coronary heart disease, and cerebrovascular diseases were excluded by laboratory and imaging examinations, as well as those with neoplastic diseases and autoimmune diseases.

Design outcomes

Primary

MeasureTime frame
Methylation level of ABCG1 promoter;

Countries

China

Contacts

Public ContactXin Wang

The Affiliated Hospital of Inner Mongolia Medical University

wxgood2016@163.com+86 178 3526 2134

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026