None
Conditions
Interventions
Remimazolam besylate group:None
Sponsors
Shijiazhuang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years, regardless of gender; 2. Requiring procedural examinations due to clinical conditions, and in need of sedation during the procedure (sedation target: RASS score -2 to 0); 3.Voluntarily participating in the study and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with primary life-threatening diseases, including unresectable malignant tumors with multiple metastases due to uncontrolled progression, hematological diseases, etc. 3. Patients who have continuously used immunosuppressants or undergone organ transplantation within the past 6 months; 4. Patients with known hypersensitivity to remimazolam besylate, propofol, or their excipients; 5. Severe hepatic or renal failure (liver function: Child-Pugh class C renal function: creatinine clearance < 10 mL/min, or requiring unstable renal replacement therapy); 6. Patients unable to complete analgesia and sedation assessment due to severe psychiatric history, schizophrenia, severe depression, end-stage disease, or any other conditions that interfere with the accurate evaluation of cognitive function; 7. Patients who participated in other clinical trials within the past 3 months; 8.Patients judged by the investigators as unable to complete or unsuitable for enrollment in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation onset time;Incidence of adverse reactions during the study period;Stability of sedation maintenance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time;Vital signs(Systolic blood pressure (SBP)?Diastolic blood pressure (DBP)?Heart rate (HR)?Respiratory rate (RR)?Pulse oxygen saturation (SpO?)); | — |
Countries
China
Contacts
Public ContactXue Qian
Shijiazhuang People's Hospital
Outcome results
None listed