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The monitoring role of ctDNA in the efficacy of maintenance therapy after hematopoietic stem cell transplantation in patients with malignant lymphoma

The monitoring role of ctDNA in the efficacy of maintenance therapy after hematopoietic stem cell transplantation in patients with malignant lymphoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122702
Enrollment
Unknown
Registered
2026-04-16
Start date
2026-04-17
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphoma

Interventions

Observation group:None

Sponsors

Shanghai Ninth People's Hospital,Shanghai JiaoTong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Male or female, aged 18 to 65 (including both 18 and 65); 2.For patients diagnosed with malignant lymphoma, after completing standard treatment in accordance with the diagnosis and treatment guidelines and achieving complete remission (CR), autologous hematopoietic stem cell transplantation was performe; 3.All patients must have given informed consent to this study and have voluntarily signed a written informed consent form by themselves (or their legal representatives);

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women who have the ability to reproduce but refuse to take contraceptive measures; 2.History of other malignant tumors except malignant lymphoma, unless the patient's disease has been cured for more than 3 years; 3.Any past or current diseases, treatments, or laboratory abnormalities that may interfere with the research results or affect the patient's full participation in the study, or any conditions that the researcher deems the patient unsuitable to participate in this study;

Design outcomes

Primary

MeasureTime frame
Progression free survival;

Secondary

MeasureTime frame
Overall survival after transplantation;Changes in ctDNA before and after transplantation;

Countries

China

Contacts

Public ContactJun Shi

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine

junshi@sjtu.edu.cn+86 13701867597

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026