postoperative analgesia after gynecologic laparoscopy or abdominal surgery
Conditions
Interventions
Experimental group:PCIA regimen
The PCIA pump was set as follows: tegileridine 3 mg, flurbiprofen axetil 100 mg, ondansetron 8 mg, dexamethasone 5 mg, and haloperidol 1 mg were diluted to a total volu
Control group:PCIA regimen
The PCIA pump was prepared as follows: sufentanil 30 µg, nalbuphine 20 mg, ketorolac tromethamine 60 mg, ondansetron 8 mg, dexamethasone 5 mg, and haloperidol 1 mg were dilu
Sponsors
Maternal and Child Health Hospital of Jiangxi Province
Eligibility
Sex/Gender
Female
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Female patients aged 18–65 years, with ASA physical status I–III, scheduled for elective gynecological laparoscopic or open surgery, and who had provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing myomectomy or adenomyomectomy; 2. Hypersensitivity to the study drugs; 3. Long-term use of opioids (>1 week); 4. Severe hepatic or renal dysfunction, chronic intestinal obstruction, or inflammatory bowel disease; 5. Uncorrected nausea, vomiting, or severe constipation before surgery; 6. Use of antiemetics or prokinetic agents within 24 hours preoperatively; 7. History of opioid or alcohol abuse; 8. Mental or cognitive disorders that prevent cooperation with assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first flatus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of nausea, vomiting, and dizziness within 24–48 hours postoperatively.;Numerical Rating Scale (NRS) scores at rest and during activity at 24?h and 48?h postoperatively.;The number of effective PCIA compressions, total analgesic solution consumption, and the number of cases requiring rescue analgesia within 24 h and 48 h postoperatively were recorded.; | — |
Countries
China
Contacts
Public ContactLi Huanhuan
Jiangxi Maternal and Child Health Hospital
Outcome results
None listed