Alzheimer's Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Educational attainment of primary school or above, aged 55–100 years, with no restrictions on marital status or occupation; 2. Adequate vision and hearing to complete the examinations; 3. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe physical diseases; 2. Mental illnesses that prevent the subject from cooperating with assessments; 3. Neurological disorders including stroke, traumatic brain injury, epilepsy, etc.; 4. Subjects with disturbance of consciousness, language impairment, or physical disability who cannot cooperate with relevant evaluations; 5. Life-threatening severe illnesses; 6. Severe visual or hearing impairment, or other conditions that interfere with communication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolite profile of blood specimens;Microbiota characteristics of fecal specimens;Score on the Montreal Cognitive Assessment-Basic (MoCA-B); | — |
Secondary
| Measure | Time frame |
|---|---|
| General demographic data (age, smoking history, drinking history, educational level, marital status, history of hypertension, history of diabetes);Body measurement indicators;Laboratory test indicators (blood routine, liver function, kidney function, blood lipid, thyroid function, inflammation and metabolic indicators); | — |
Countries
China
Contacts
Affiliated Kangning Hospital of Ningbo University