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Impact of Baseline Astigmatism on the Myopia Control Efficacy of Contrast-Reducing versus Defocus Lenses: A Real-World Retrospective Cohort Study

Impact of Baseline Astigmatism on the Myopia Control Efficacy of Contrast-Reducing versus Defocus Lenses: A Real-World Retrospective Cohort Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122618
Enrollment
Unknown
Registered
2026-04-15
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

HAL group:None
DOT group:None

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 16 Years

Inclusion criteria

Inclusion criteria: 1.Aged between 3 and 16 years at the time of first prescription of the target lenses; 2.Baseline spherical equivalent refraction (SER) between -0.50 D and -8.00 D; 3.With or without different degrees of regular astigmatism (astigmatism >=0 D); 4.Regular wear of contrast-reducing lenses (DOT) or multi-point defocus lenses (HAL); 5.Complete baseline data and at least 3 months of follow-up data available;

Exclusion criteria

Exclusion criteria: 1.Complicated with binocular vision dysfunction such as amblyopia and strabismus; 2.Suffering from other severe ocular or systemic diseases; 3.Concomitant use of other myopia control interventions; 4.Poor compliance or obvious logical errors in core clinical medical records;

Design outcomes

Primary

MeasureTime frame
Annualized axial length (AL) change rate (mm/year);

Secondary

MeasureTime frame
Annualized spherical equivalent refraction (SER) change rate (D/year);

Countries

China

Contacts

Public ContactLu, Yi

Shanghai General Hospital

yiyiscorpio@163.com+86 21 63240090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026