Infertility
Conditions
Interventions
Remimazolam group (R group) :None
Ciprofol group (C group) :None
Sponsors
Shanghai First Maternity and Infant Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 42 Years
Inclusion criteria
Inclusion criteria: 1. ASA physical status I-II; 2. age 21-42 years; 3. weight 50-77 kg; 4. body mass index (BMI) 18-31 kg/m^2
Exclusion criteria
Exclusion criteria: 1. Uncontrolled blood pressure; 2. Psychiatric disorders; 3. Severe respiratory disease; 4. History of drug abuse or alcohol abuse within 2 years before screening; 5. Use of benzodiazepines and/or opioids for nearly 3 months; 6. Allergy or contraindication to benzodiazepines, opioids, propofol, and their components.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vital signs (BP, HR, SpO2, BIS);Clinical indicators (onset of anesthesia, emergence time, oocyte retrieval duration, postoperative orientation recovery time);Analgesic effect (pain VAS score after ovarian puncture and follicular fluid aspiration);Adverse events (incidence of hypotension, bradycardia, nausea/vomiting, dizziness, respiratory depression); | — |
Secondary
| Measure | Time frame |
|---|---|
| Anesthesia and surgical duration (onset of anesthesia, surgery duration, emergence time);Postoperative recovery quality (orientation recovery time within 30 minutes postoperatively, pain VAS scores at emergence, 15 minutes post-emergence, and 30 minutes post-emergence);Postoperative adverse events (incidence of dizziness, nausea, vomiting); | — |
Countries
China
Contacts
Public ContactLi Haibing
Shanghai First Maternity and Infant Hospital
Outcome results
None listed