Postoperative pain
Conditions
Interventions
Bupivacaine liposome group:performing unilateral L4 level anterior quadratus lumborum block using 0.4ml/kg of liposome bupivacaine (266mg/30ml), maximum 30 ml.
Control group:Without performing the anterior quadratus lumborum block, apply a sterile dressing patch at the block site.
Sponsors
Affiliated Hospital of Jiangsu University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Undergoing direct anterior approach total hip arthroplasty under general anesthesia due to hip fractures; 2. Aged 65-80 years old; 3.Body mass index 18-30kg/m^2; 4.Can fully understand the research content; 5.ASA classification I-III.
Exclusion criteria
Exclusion criteria: 1.History of hip surgery; 2. Allergy to local anesthetics; 3. Abnormal coagulation function; 4.Infection near the puncture site; 5. History of opioid or alcohol abuse; 6. Chronic pain or undergoing chronic pain treatment; 7.Preoperative coexisting heart failure, severely reduced respiratory function,severe arrhythmia, poorly controlled hypertension, diabetes and other underlying diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sufentanil consumption 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 Rating Scale;Sufentanil consumption 48 and 72 hours after surgery;The consumption of remifentanil and propofol during the operation;Timing of first postoperative patient-controlled analgesia;Postoperative pain numerical scale score;Time to first ambulation;Lower limb muscle strength;Adverse reaction; | — |
Countries
China
Contacts
Public ContactWu Jin
Affiliated Hospital of Jiangsu University
Outcome results
None listed