quality of recovery
Conditions
Interventions
Group C:ciprofol : induction (0.5 mg/kg) + maintenance(1.25mg/kg/h)
Group RF:Remimazolam-flumazenil : induction (0.25 mg/kg) + maintenance (1 mg/kg/h), with flumazenil 0.5 mg administered at the end of surgery.
Group RS:emimazolam-saline : induction (0.25 mg/kg) + maintenance (1 mg/kg/h), with normal saline administered at the end of surgery.
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Signed the informed consent form; 2. Scheduled for elective gynecological day surgery; 3. Classified as ASA grade I-II; 4. BMI 18.5-27.9 kg/m^2; 5. Aged 18 to 65 years.
Exclusion criteria
Exclusion criteria: 1. Allergy to study drugs; 2. Long-term use of benzodiazepines or opioids; 3. Severe hepatic or renal insufficiency; 4. Uncontrolled hypertension or heart disease; 5. Pregnancy or lactation; 6. History of substance abuse; 7. Difficulty in communication or compliance with follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time from discontinuation of drug administration to eye opening.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic changes during anesthesia.;Incidence of adverse events during anesthesia.;Incidence of adverse events within 24 hours postoperatively.;Patient satisfaction.; | — |
Countries
China
Contacts
Public ContactFanceng Ji
Weifang People's Hospital, Shandong Province
Outcome results
None listed