Stroke
Conditions
Interventions
High intensity interval training:High-intensity interval training (80-90% HRpeak) was performed using a limb-linkage training device for 25 minutes per session, 3 sessions per week, over a period of 3
Moderate intensity continuous training:Moderate-intensity continuous training (46-64% HRpeak) was conducted using a limb-linkage training device. The training program lasted for 3 weeks, with each ses
Conventional treatment:Basic disease drug treatment, routine rehabilitation treatment, and routine cognitive function training, etc
Sponsors
Shaanxi Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for stroke (as defined by the Chinese Stroke Prevention and Treatment Guidelines 2021 and confirmed by neuroimaging examinations such as CT or MRI). 2. First stroke onset, age between 25 and 75 years. 3. Montreal Cognitive Assessment (MoCA) score = 6 months. 5. Muscle strength of the affected side = grade 3 (Manual Muscle Testing), capable of completing cardiopulmonary exercise testing. 6. Demonstrates good compliance, voluntarily participates, and has obtained consent from family members.
Exclusion criteria
Exclusion criteria: 1. Patients with severe concurrent cardiovascular conditions related to stroke, such as severe heart failure, angina pectoris, acute myocardial infarction, atrial fibrillation, or severe emphysema. 2. Patients with severe infections, significant dysfunction of vital systems (e.g., pulmonary, hepatic, renal, endocrine, or hematopoietic systems), or severe comorbidities such as osteoporosis, fractures, or arthropathy. 3. Patients with hemodynamic instability, including uncontrolled hypertension. 4. Patients with severe speech, visual, auditory, or psychiatric disorders that may affect cognitive function. 5. Patients diagnosed with post-stroke cognitive impairment (PSCI), such as dementia, prior to enrollment—as confirmed by medical records, clinicians, or family members—or those already using cognition-enhancing medications (e.g., Donepezil, Memantine) recommended with Class I–IIa, Level A–B evidence in the 2021 Chinese Expert Consensus on Post-Stroke Cognitive Impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive ;Trail Making Test - Part A;Trail Making Test - Part B;Clock Drawing Test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel Index; | — |
Countries
China
Contacts
Public ContactChen Longwei
Shaanxi Rehabilitation Hospital
Outcome results
None listed