Hyperthyroidism
Conditions
Interventions
Observation group:None
Sponsors
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-65 years, regardless of gender, with no pregnancy plans in the coming year; 2.Diagnosed with hyperthyroidism according to the Guidelines for Diagnosis and Treatment of Hyperthyroidism; 3.Treated with antithyroid drugs (ATD) under a standardized treatment regimen; 4.Willing to participate in the study and provide written informed consent;
Exclusion criteria
Exclusion criteria: 1.Patients with comorbidities such as diabetes mellitus, hypertension, metabolic syndrome, cardiovascular diseases, malignancies, or other autoimmune-related disorders; 2.Patients with hepatic insufficiency: alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels exceeding twice the upper limit of normal; 3.Patients with renal insufficiency: glomerular filtration rate (GFR) < 90 mL/min/1.73m^2; 4.Patients with a history of allergy to antithyroid drugs; 5.Patients with acute infections; 6.Pregnant or lactating women; 7.Patients with alcohol abuse; 8.Patients participating in other drug or interventional studies; 9.Patients who did not receive adequate follow-up or withdrew from the study prematurely;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Cholesterol (TC);High-Density Lipoprotein Cholesterol (HDL-C);Low-Density Lipoprotein Cholesterol (LDL-C);Triglycerides (TG); | — |
Secondary
| Measure | Time frame |
|---|---|
| Anaphylaxis;Fasting insulin (FINS);Aspartic transaminase(AST);Alanine aminotransferase(ALT);Rash;Insulin resistance index;Fasting blood glucose (FBG);Neutrophile granulocyte; | — |
Countries
China
Contacts
Public ContactRongxueYang
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed