Acute Mountain Sickness
Conditions
Interventions
Experimental group:Cardiopulmonary Exercise Test (CPET) Combined with High-Altitude Exposure in Hypobaric Hypoxia Chamber
Sponsors
Shanghai Yangzhi Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Subjects are healthy adults aged 18-40 years, 2. Permanent residents of plains (living at an altitude <1500 meters, not having entered areas above 2500 meters in the past 6 months), 3. No history of smoking or alcohol abuse, previously healthy, with no other major disease history (cardiovascular, cerebrovascular, respiratory systems), 4. No history of high-altitude illness (such as cerebral edema), 5. Currently not using medications that affect cardiovascular or pulmonary diseases.
Exclusion criteria
Exclusion criteria: 1.With a history of major diseases; 2.With a history of severe acute mountain sickness; 3.Unable or unwilling to cooperate with the study procedures;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Discriminative ability of the predictive model (test set AUC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;specificity;accuracy;calibration curve (Brier score);feature importance ranking (GBDT built-in importance, SHAP values); | — |
Countries
China
Contacts
Public ContactShang Yunlin
Shanghai Yangzhi Rehabilitation Hospital
Outcome results
None listed