Non-clinical population
Conditions
Interventions
Intervention Group:On the basis of the basic public health services of the aforementioned countries, guidance services for the nurturing and care of infants and young children should be added.
Control Group:Child health care personnel in township health centers/community health service centers of sub-districts shall provide corresponding services in accordance with the contents of the Natio
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 2 Years
Inclusion criteria
Inclusion criteria: 1.16–17 months; 2.Healthy full-term infants (>=37 completed gestational weeks), singletons, and not been diagnosed by any authoritative institution with global developmental delay or any other significant medical condition; 3.Each child had a consistent primary caregiver, who was aged 65 years or younger, and neither the child nor the primary caregiver had plans to relocate from the local area within the next 12 months. 4.The primary caregiver was willing to participate in the project and able to attend follow-up visits as scheduled.
Exclusion criteria
Exclusion criteria: 1.The child had a history of birth trauma, intrauterine/perinatal/postnatal asphyxia, hypoxic-ischemic encephalopathy, or intracranial hemorrhage. 2.The child's parents or siblings had been diagnosed with neurological disorders, psychiatric or developmental conditions, or other chronic illnesses that would make them unsuitable for studies on brain development and function. 3.The primary caregiver had been diagnosed with a psychiatric or neurological disorder, such as depression or schizophrenia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain and cognitive developmental level;Brain structural plasticity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting-state functional connectivity;Neural synchrony;Electrophysiological measures;Salivary cortisol levels;Hair cortisol concentration;Quality of parent–child interaction;Assessment of caregiving and the family environment;Assessment of the home language environment;Anemia screening; | — |
Countries
China
Contacts
Public ContactJiang Fan
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed