bulimia nervosa
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Outpatients or inpatients meeting the DSM-5 diagnostic criteria for bulimia nervosa; 2. Age 18–45 years (>=18 and <=45); 3. Normal vision or corrected vision, no claustrophobia, no metal implants in the body.
Exclusion criteria
Exclusion criteria: 1. Individuals with current substance abuse or dependence, including alcohol or other psychoactive substances; 2. Individuals with severe somatic illnesses that prevent completion of follow-up; 3. Individuals previously diagnosed with or co-occurring with other severe psychiatric disorders meeting ICD-10 or DSM-5 diagnostic criteria, intellectual disability, dementia, and severe cognitive impairment; 4. Individuals with current or past major somatic diseases, neurological disorders, or brain injuries that may affect brain structure or function; 5. Individuals with suicidal tendencies or poor cooperation; 6. Individuals with metallic implants in the body or other conditions that are not suitable for magnetic resonance imaging (MRI); 7. Pregnant or breastfeeding women; 8. Individuals with intracranial metal, electronic devices, a history of epilepsy, or a family history of epilepsy, or other contraindications for transcranial magnetic stimulation (TMS); 9. Other abnormal findings identified by the investigators that are considered unsuitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain activity signals; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peripheral biomarker levels;depression, anxiety, impulsivity, and symptoms related to eating behaviors; | — |
Countries
China
Contacts
Hangzhou Seventh People's Hospital