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Brain Functional and Structural Alterations in Individuals with Bulimia Nervosa: A 7-Tesla Magnetic Resonance Imaging Study

Brain Functional and Structural Alterations in Individuals with Bulimia Nervosa: A 7-Tesla Magnetic Resonance Imaging Study

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122542
Enrollment
Unknown
Registered
2026-04-15
Start date
2026-02-10
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bulimia nervosa

Interventions

control group (individuals without psychiatric diseases):none
experimental group (individuals with bulimia nervosa):none

Sponsors

Hangzhou Seventh People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Outpatients or inpatients meeting the DSM-5 diagnostic criteria for bulimia nervosa; 2. Age 18–45 years (>=18 and <=45); 3. Normal vision or corrected vision, no claustrophobia, no metal implants in the body.

Exclusion criteria

Exclusion criteria: 1. Individuals with current substance abuse or dependence, including alcohol or other psychoactive substances; 2. Individuals with severe somatic illnesses that prevent completion of follow-up; 3. Individuals previously diagnosed with or co-occurring with other severe psychiatric disorders meeting ICD-10 or DSM-5 diagnostic criteria, intellectual disability, dementia, and severe cognitive impairment; 4. Individuals with current or past major somatic diseases, neurological disorders, or brain injuries that may affect brain structure or function; 5. Individuals with suicidal tendencies or poor cooperation; 6. Individuals with metallic implants in the body or other conditions that are not suitable for magnetic resonance imaging (MRI); 7. Pregnant or breastfeeding women; 8. Individuals with intracranial metal, electronic devices, a history of epilepsy, or a family history of epilepsy, or other contraindications for transcranial magnetic stimulation (TMS); 9. Other abnormal findings identified by the investigators that are considered unsuitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Brain activity signals;

Secondary

MeasureTime frame
Peripheral biomarker levels;depression, anxiety, impulsivity, and symptoms related to eating behaviors;

Countries

China

Contacts

Public ContactJianbao Wang

Hangzhou Seventh People's Hospital

jianbaoking@zju.edu.cn+86 571 85126521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026