Retinal Vein Occlusion Macular Edema
Conditions
Interventions
Gold Standard:Gold Standard for Diagnosing RVO (BRVO/CRVO): Fluorescein Angiography (FFA)
1. Branch Retinal Vein Occlusion (BRVO)
Tortuosity and dilation of a retinal vein
Patchy hemorrhage and edema
Index test:Optical coherence tomography (OCT),?wide-field OCTA,?microperimeter
Sponsors
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years. 2.Diagnosis of RVO (BRVO or CRVO); 3.Macular edema (CST >=325 µm) involving the fovea, secondary to RVO. BCVA between 73 and 25 letters (ETDRS); 4.For patients who, owing to their medical condition, have determined to undergo Conbercept injection therapy, the informed consent form ought to be revised concurrently. 5.Those who have signed the informed consent;
Exclusion criteria
Exclusion criteria: 1.Active ocular inflammation or suspected/active ocular or periocular infection in either eye. 2.Concurrent vitreous hemorrhage, tractional retinal detachment, or epiretinal membrane involving the macular structure. 3.Uncontrolled glaucoma. 4.Any anti-VEGF therapy in the study eye within the preceding 3 months. 5.Any intravitreal (IVT), periocular, or implanted corticosteroid therapy, or use of any Iluvien® implant within the preceding 6 months. 6.Any cataract surgery within the preceding 3 months, or a history of other intraocular surgeries such as vitrectomy; 7.Individuals with mental illnesses or other medical conditions that prevent them from cooperating with surgery and follow-up; 8.Patients with poor communication skills and poor adherence; 9.Participate in other clinical trials;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity (BCVA); | — |
Secondary
| Measure | Time frame |
|---|---|
| CST;MS; | — |
Countries
China
Contacts
Public ContactXiling Yu
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Outcome results
None listed