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Study on the diagnostic value of ultrasound-derived fat fraction combined with skeletal muscle elastography in sarcopenia among the elderly

Study on the diagnostic value of ultrasound-derived fat fraction combined with skeletal muscle elastography in sarcopenia among the elderly

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122513
Enrollment
Unknown
Registered
2026-04-14
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia

Interventions

Gold Standard:Sarcopenia assessment: According to the diagnostic criteria for sarcopenia in the Chinese Expert Consensus on the Prevention and Control of Sarcopenia in the Elderly (2023), improve the
Index test:Name of the diagnostic test to be evaluated: Skeletal muscle ultrasound examination Examination positions: Examine the gastrocnemius, soleus (in the prone position), and quadriceps femoris

Sponsors

Zhongda Hospital Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Inpatients aged between 60 and 80 years old; 2. The medical records are complete, the patients have good compliance, and they agree to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Have used nutritional supplements within the last three months; have been taking medications such as thyroid tablets, methimazole, propylthiouracil, steroids, and estrogen-progesterone for a long time. 2. Disabled patients with dementia, intellectual disability, or low cognitive function; patients who are bed-ridden for a long time, have limb disabilities, suffer from rheumatological immune system diseases, neurological diseases, or bone and joint diseases and are unable to undergo muscle strength and function assessments. 3. Patients with severe cardiopulmonary insufficiency (referring to those who cannot carry out normal daily activities; with a New York Heart Association (NYHA) heart failure classification of III or IV, or those who cannot complete a 6-meter walking test), patients in the terminal stage of malignant tumors, and patients with severe infectious diseases. 4. Patients with implanted cardiac pacemakers, cardiac defibrillators, or joint replacements who cannot undergo BIA (Bioelectrical Impedance Analysis) and MRI (Magnetic Resonance Imaging) examinations.

Design outcomes

Primary

MeasureTime frame
Ultrasound-derived fat fraction;Accuracy;

Secondary

MeasureTime frame
magnetic resonance imaging proton density fat fraction;Muscle ultrasound parameters;Muscle elastography;Sensitivity;Specificity;

Countries

China

Contacts

Public ContactAn Li

Zhongda Hospital Southeast University

alywr@live.cn+86 136 4515 6180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026