Major cardiovascular, pulmonary, and cerebral diseases in plateau regions
Conditions
Interventions
Observational group (Risk Assessment Group / Dynamic Adaptation Group (Plateau Period) / Patient Group):None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Risk Assessment Group (Before Entry): (1) Aged 18-60 years; (2) Planning to work or live in high-altitude areas (elevation >= 2,500 meters) within the next 3 months; (3) Sign the informed consent form; 2. Dynamic Adaptation Group (During Highland Period): (1) Having continuously lived in high-altitude areas for no more than 1 year, or after members of the included risk assessment group enter the highlands; (2) Aged 18-75 years; (3) Sign the informed consent form; 3. Patient Group: (1) Clinically diagnosed with major cardiopulmonary or cerebrovascular diseases such as high-altitude pulmonary edema, high-altitude cerebral edema, or high-altitude heart disease; (2) Aged >=18 years; (3) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with severe mental illnesses or cognitive impairments who are unable to cooperate with the research process; 2. Pregnant or breastfeeding women (due to potential risks of certain examinations); 3. Patients with advanced malignant tumors or other end-stage diseases with an expected survival of less than 1 year; 4. Other situations deemed by the researcher as unsuitable for participation in this study (such as long-term alcoholism, drug abuse, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major cardiopulmonary and cerebrovascular diseases occurrence;Outcomes;History of high altitude Travel and Residence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease severity;Demographics(Permanent residence altitude, duration on the altitude, etc.);Vital signs;Medical history;Physical examination;Laboratory test(blood routine, biochemistry, myocardial enzyme spectrum, coagulation function, etc.);Imaging data (e.g., chest X-ray, echocardiography,PFT;Wearable device monitoring data (e.g.,blood oxygen saturation, cerebral oxygen saturation, heart rate, blood pressure, pulmonary artery pressure);Telemedicine records; | — |
Countries
China
Contacts
Public ContactFengming Luo
West China Hospital, Sichuan University
Outcome results
None listed