Breast Cancer
Conditions
Interventions
Cancer Therapy-Related Cardiac Dysfunction:None
None Cancer Therapy-Related Cardiac Dysfunction:None
Sponsors
The Second Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Breast cancer patients who have received chemotherapy, targeted therapy, or surgical treatment; 2. Age: 18 to 85 years old; 3. The patient's expected survival period is greater than 12 months; 4. Patients with good compliance who voluntarily accept follow-up.
Exclusion criteria
Exclusion criteria: 1. Due to the severity of the condition, the patient is unable to tolerate the assessment of cardiac structure and function through imaging. 2. Have a history of drug abuse; 3. Inability to regularly follow up and recheck blood biomarkers and imaging indicators; 4. End-stage renal failure (defined as glomerular filtration rate less than 15ml/min.m2); 5. Combined with other malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time from first presentation to all-cause or cardiovascular disease-related rehospitalization;Time from first presentation to all-cause or cardiovascular disease-related death;Change in left ventricular ejection fraction (LVEF) level;Changes in cardiac structural parameters, including left ventricular end-diastolic diameter (LVEDD), left atrial diameter, and four-chamber atrial diameter, etc.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular Disease Risk Assessment Form;Eastern Cooperative Oncology Group (ECOG) Performance Status Scale; | — |
Countries
China
Contacts
Public ContactZhang Yang
The Second Affiliated Hospital of Dalian Medical University
Outcome results
None listed