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Effect of High-Intensity Interval Training on Cardiovascular Health in Stroke Patients: A Randomized Controlled Trial

Effect of High-Intensity Interval Training on Cardiovascular Health in Stroke Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122479
Enrollment
Unknown
Registered
2026-04-14
Start date
2026-04-20
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

High-Intensity Interval Training (HIIT):The exercise was performed on a limb linkage training device. The intensity was set at 80%–90% of Peak Heart Rate Reserve (PHR). Each session consisted of 3–4 r
Moderate-Intensity Continuous Training (MICT) :The exercise was performed on a limb linkage training device. The intensity was set at 40% of Peak Heart Rate Reserve (PHR), with each session lasting 30
Conventional treatment (CT):The conventional treatment group received only conventional physical therapy and was permitted to engage in routine daily physical activities, but did not participate in an

Sponsors

Shaanxi Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for stroke (according to the Chinese Guidelines for Stroke Prevention and Treatment 2021, confirmed by neuroimaging examinations such as CT or MRI); 2. First stroke onset and currently within the 6–12 month recovery period, age between 40 and 80 years (inclusive); 3. Able to walk independently for at least 10 meters; 4. Capable of understanding instructions and cooperating with the training program; 5. Demonstrates good compliance, voluntarily participates, and has obtained consent from family members.

Exclusion criteria

Exclusion criteria: 1. Modified Rankin Scale score > 2 points; 2. Patients with contraindications to exercise testing; 3. Patients meeting American Heart Association Class C or D risk criteria; 4. Patients with other neurological or musculoskeletal comorbidities that preclude exercise participation; 5. Patients experiencing exacerbated pain following exercise; 6. Patients with cognitive, communication, or behavioral issues that may limit their ability to provide informed consent or follow rehabilitation therapist instructions.

Design outcomes

Primary

MeasureTime frame
Left ventricular ejection fraction;Left ventricular end-diastolic volume;Left ventricular end-diastolic diameter;Left ventricular mass;Left atrial volume index;Mitral valve E/A ratio;Systolic blood pressure;Diastolic blood pressure;High-sensitivity cardiac troponin (hs-cTnT / hs-cTnI);N-terminal pro-B-type natriuretic peptide (NT-proBNP);High-sensitivity C-reactive protein (hs-CRP);

Secondary

MeasureTime frame
Six-minute walk (6MWT);10-meter walk speed (10MWS);

Countries

China

Contacts

Public ContactChen Longwei

Shaanxi Rehabilitation Hospital

3124331009@stu.xjtu.edu.cn+86 180 6676 3885

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026