Complications of painless gastroscopy
Conditions
Interventions
Group A (18-30y):HFNO was administered at 30 L/min 1 minute before anesthesia. For each subsequent patient, the flow rate of HFNO was increased or decreased by 5 L/min based on whether the previous pa
Group B (31-40y):HFNO was administered at 30 L/min 1 minute before anesthesia. For each subsequent patient, the flow rate of HFNO was increased or decreased by 5 L/min based on whether the previous pa
Group C (41-50y):HFNO was administered at 30 L/min 1 minute before anesthesia. For each subsequent patient, the flow rate of HFNO was increased or decreased by 5 L/min based on whether the previous pa
Group D (51-60y):HFNO was administered at 30 L/min 1 minute before anesthesia. For each subsequent patient, the flow rate of HFNO was increased or decreased by 5 L/min based on whether the previous pa
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 18-60 years; 2.BMI: 18-25 kg/m^2; 3.ASA class I-II; 4.Mallampati class I-II without head/neck mobility impairment; 5.Voluntarily agree to participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of cardiovascular/cerebrovascular or pulmonary diseases; 2. Hepatic or renal insufficiency; 3. Obstructive sleep apnea syndrome (OSAS); 4. Acute upper gastrointestinal hemorrhage; 5. Pregnancy or lactation; 6. Hypersensitivity to anesthetic agents; 7. Current enrollment in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The median effective oxygen flow and 95% confidence interval of HFNC in preventing hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs (perioperative blood pressure, heart rate, and respiratory rate (at 5 minutes before anesthesia induction (T0), 1 minute after anesthesia (T1), and 5 minutes after anesthesia (T2));Complications (respiratory desaturation (90% = SpO2= 94%);nausea or vomiting; nasal discomfort or bleeding);Total dose of propofol;Arterial blood gas partial pressures (PaCO2, PaO2, pH performed preoperatively, at the onset of hypoxemia, or postoperatively.);Gastroscopy operation time;Wake-up time;Intraoperative water irrigation volume;Patients' baseline characteristics (age, gender, height, weight, BMI, tracheal diameter);The operation time for gastroscopy; | — |
Countries
China
Contacts
Public ContactCai Chengyi
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed