Colorectal cancer
Conditions
Interventions
Control group:Sham transcutaneous auricular vagus nerve stimulation combined with patient-controlled intravenous analgesia
Experimental group:Transcutaneous Auricular Vagus Nerve Stimulation Combined with Patient-Controlled Intravenous Analgesia
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.ASA physical status classification Class I-III; 2.Age >=18 years old; 3.Patients scheduled for elective laparoscopic colorectal cancer surgery.
Exclusion criteria
Exclusion criteria: 1.Refusal to sign the informed consent form. 2.Patients who decline postoperative patient-controlled intravenous analgesia (PCIA). 3.Preoperative history of documented neurological or psychiatric disorders. 4.Individuals on long-term psychotropic medication for depression, anxiety, or sleep disorders. 5.Individuals with a history of chronic pain or long-term use of analgesics. 6.Abnormality at the ear stimulation site; 7.Concurrent use of other electrical stimulation devices (e.g., cardiac pacemakers). 8.Concomitant presence of severe respiratory diseases, severe cardiovascular or cerebrovascular diseases, severe hepatic insufficiency, or severe renal insufficiency. 9.Previous colorectal surgery; 10.Concurrent participation in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the curve (AUC) of visual analog scale pain scores within 48 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative adverse events;Visual Analog Scale (VAS) pain scores on postoperative days 3 and 7;Anxiety, depression, and sleep scores on postoperative days 1, 3, and 7;Time to first passage of flatus postoperatively;NRL and CRP on postoperative days 1, 3, and 7;Recovery quality on postoperative day 7.;Number of patient-controlled analgesia (PCA) demands postoperatively; | — |
Countries
China
Contacts
Public ContactShen Wen
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed