Chronic apical periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years (inclusive), regardless of gender. 2. Patients with chronic apical periodontitis in anterior or premolar teeth exhibiting closed apical foramina. 3. Teeth with a periapical radiolucency diameter <=5 mm. 4. Subjects voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe systemic diseases. 2. Individuals with mental disorders or cognitive dysfunction who are unable to cooperate. 3. Patients with a cardiac pacemaker. 4. Patients with malignant tumors or those who have undergone radiotherapy in the head and neck region. 5. Teeth that have previously received root canal treatment. 6. Teeth presenting with root fracture, calcified root canal, root resorption, severe periodontal disease, or a sinus tract. 7. Teeth with mobility = Grade II. 8. Patients with severe bruxism or malocclusion. 9. Individuals who have used antibiotics within the past week. 10. Patients with radicular cysts. 11. Women who are pregnant, lactating, or planning pregnancy within the next three months. 12. Individuals who have participated in another clinical trial within the past three months. 13. Individuals deemed by the investigator to be unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absence or reduction rate of percussion pain after root canal irrigation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement rate of periapical tissue imaging;VAS pain score;Post-obturation percussion pain;Tooth mobility; | — |
Countries
China
Contacts
Xuanwu Hospital Capital Medical University