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The influence of pulp calcification and hemostasis time on the prognosis of partial pulpotomy in mature permanent teeth with irreversible pulpitis: A retrospective cohort study

The influence of pulp calcification and hemostasis time on the prognosis of partial pulpotomy in mature permanent teeth with irreversible pulpitis: A retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122445
Enrollment
Unknown
Registered
2026-04-14
Start date
2026-04-14
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible pulpitis

Interventions

Non-calcified group:None
Calcified group:None

Sponsors

Shanghai Stomatological Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.The first and second permanent molars with closed apical foramina in adult patients (aged 18 years and above). 2. There is a history of cold or hot stimulation pain and/or spontaneous pain, and the clinical diagnosis is irreversible pulpitis. Clinical examination shows positive responses to cold/hot tests, accompanied by delayed pain. 3. The X-ray examination revealed deep caries and pulp involvement, but there was no low-density shadow in the periapical tissues. 4. The surgical procedure was PP (i.e., removing carious tissue and exposing the pulp, followed by performing PP). After treating the pulp wound with a 2.5% hypochlorous acid solution, hemostasis could be achieved within 10 minutes. 5. Follow-up period of at least 1 year.

Exclusion criteria

Exclusion criteria: 1.The electrical vitality test showed no response. 2. After undergoing the cavity-filling treatment, it was discovered that the dental pulp had necrotized. 3. Cases where the surgical procedure was total pulp resection. 4. Cases where bleeding could not be controlled during the operation and root canal treatment had to be performed instead; 5. Diagnosed as irreversible pulpitis due to reasons such as tooth wear, wedge-shaped defects, tooth cracks, and periodontal disease. 6. Suffering from moderate to severe periodontitis or root bifurcation lesions. 7. Patients during pregnancy or lactation period who are unable to cooperate due to physical or mental disorders.

Design outcomes

Primary

MeasureTime frame
Treatment success rate;

Secondary

MeasureTime frame
Prognostic factors;

Countries

China

Contacts

Public ContactMa Zhifei

Shanghai Stomatological Hospital, Fudan University

mazf1017@163.com+86 21 6360 1092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026