chronic constipation
Conditions
Interventions
control group:sacral magnetic stimulation+transcutaneous auricular sham stimulation
experimental group:transcutaneous auricular vagus nerve stimulation+sacral magnetic stimulation
Sponsors
Beijing Haidian Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–80 years old; 2. Meet the Rome IV criteria and the "Chinese Clinical Guidelines for the Diagnosis and Treatment of Chronic Constipation": bowel movements less than 3 times per week, difficulty in defecation, straining, small stool volume, may be accompanied or not by abdominal pain, bloating, anorectal pain, and other discomforts; 3. Willing to sign a written informed consent, compliant, and able to cooperate with treatment.
Exclusion criteria
Exclusion criteria: 1. Combined severe cardiovascular, respiratory system diseases, diabetes, kidney disease, and chronic diseases related to gastrointestinal problems; 2. Implanted electronic devices (e.g., pacemakers) or metal devices (e.g., metal IUDs); 3. Combined psychiatric disorders; 4. Women who are pregnant or planning pregnancy; 5. Abdominal surgery within the past 6 months; 6. Allergic reactions to surface electrodes; 7. Use of probiotics or antibiotics within 2 weeks before enrollment (to minimize effects on gut microbiota)..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characteristics of gut microbiota;Anorectal manometry;patient assessment constipation quality life ,PAC-QOL;Constipation Symptom Score;Autonomic nerve function assessment; | — |
Countries
China
Contacts
Public ContactYe Jing
Beijing Haidian Hospital
Outcome results
None listed