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A Novel Multi-Electrode Sequential Mapping Approach for Atrial Premature Complexes: Efficacy in Ablation and Differentiation from Mechanically-Induced Ectopy

A Novel Multi-Electrode Sequential Mapping Approach for Catheter Ablation of Atrial Premature Complexes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122399
Enrollment
Unknown
Registered
2026-04-13
Start date
2025-12-01
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial tachyarrhythmia

Interventions

Symptomatic atrial premature beats that have undergone catheter ablation treatment have been replaced:None

Sponsors

Wujin People's Hospital of Changzhou City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. age 19–85 years; 2. symptomatic palpitations correlated with frequent APC on 24-hour Holter monitoring (burden >10%); 3. failure or intolerance to at least one Class I or III antiarrhythmic agent; 4. APC origin confirmed by electrophysiological mapping to be non-pulmonary vein/non-superior vena cava and treated with catheter ablation.

Exclusion criteria

Exclusion criteria: 1. persistent or permanent atrial fibrillation; 2. other arrhythmias requiring concomitant ablation (e.g., typical atrial flutter, AVNRT) or chaotic atrial tachycardia; 3. left atrial diameter >55 mm or left ventricular ejection fraction <50%; 4. intracardiac thrombus, active infection, uncorrected severe electrolyte disturbances, pregnancy or lactation; 5. inability to perform catheter manipulation due to vascular anomalies or inferior vena cava filter; 6. prior cardiac surgery or atrial interventional procedure (except simple atrial septal defect closure).

Design outcomes

Primary

MeasureTime frame
Total procedure time;Premature atrial contraction burden at 3 months post-ablation;

Secondary

MeasureTime frame
Mapping time;3-month APC-free recurrence rate;Number of RF applications ;Number of instances where re-mapping;Acute Procedural Success;Complication rate;

Countries

China

Contacts

Public ContactLi Wenhua

Wujin People's Hospital of Changzhou City

64641233@qq.com+86 189 6113 7828

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026