Nasopharyngeal carcinoma
Conditions
Interventions
Nasopharyngeal carcinoma patients diagnosed by pathology and undergoing immunotherapy.:None
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Biopsy and pathological diagnosis of nasopharyngeal carcinoma confirmed. 2. First-time diagnosed patients who have not received any prior treatment. 3. Pre-treatment assessments including nasopharyngeal and cervical MRI, chest CT, abdominal CT or MRI or ultrasound, and PET-CT whole-body bone scan. 4. Patients receiving immunotherapy for nasopharyngeal carcinoma with complete follow-up data. 5. Patients with well-preserved, clearly visible tissue wax blocks. 6. Patients willing to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of other tumors or autoimmune diseases. 2. Incomplete clinical data or lack of follow-up. 3. Incomplete imaging data or poor image quality that prevents assessment of the lesion. 4. Tissue wax blocks that do not meet sectioning standards.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AUC;The time of recurrence, metastasis, and death after immunotherapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Molecular phenotypes for validating the spatial heterogeneity of TLS at the single-cell level; | — |
Countries
China
Contacts
Public ContactYuange Li
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed