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The influence of coexisting Hashimoto's thyroiditis on the therapeutic response of patients with differentiated thyroid cancer after initial treatment

The influence of coexisting Hashimoto's thyroiditis on the therapeutic response of patients with differentiated thyroid cancer after initial treatment

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122392
Enrollment
Unknown
Registered
2026-04-13
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Diseases

Interventions

non-Hashimoto's thyroiditis group:None

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Received standard initial treatment (total or near-total thyroidectomy + RAI therapy + TSH suppression therapy); 2. Postoperative pathology confirmed differentiated thyroid carcinoma (DTC); 3. Complete treatment and follow-up data are available to assess treatment response; (1) Complete initial treatment (surgery, radioactive iodine therapy) and pathological data (e.g., tumor size, lymph node metastasis) are available for ATA risk assessment. (2) Complete follow-up data (including imaging studies such as ultrasound/iodine scans, Tg/TgAb levels) are available to assess treatment response.

Exclusion criteria

Exclusion criteria: 1.Non-DTC types, including anaplastic thyroid carcinoma and medullary thyroid carcinoma; 2.Thyroid Lobectomy; 3.History of other malignant tumors; 4.Non-standard initial treatment or significantly incomplete follow-up data;

Design outcomes

Primary

MeasureTime frame
Comparison of ATA response to therapy categories between the groups with and without HT following initial treatment;The Mann-Whitney U test was used to compare differences in the distribution of treatment responses across the four categories.;

Countries

China

Contacts

Public ContactCheng Bing

The First Affiliated Hospital of Zhengzhou University

chengbing@zzu.edu.cn+86 371 66279025

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026