Acute Respiratory Failure
Conditions
Interventions
Observation group:None
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.Planned to receive HFNC therapy with an expected treatment duration > 2 hours; 3.Admitted to the ICU with hypoxemia (defined as SpO2 10 seconds, or PaO2/FiO2 < 300 mmHg); 4.Signed informed consent;
Exclusion criteria
Exclusion criteria: 1.Received invasive or non-invasive mechanical ventilation within 72 hours prior to HFNC; 2.Presence of contraindications to EIT or ultrasound; 3.Pregnant or breastfeeding; 4.Refusal of endotracheal intubation or cardiopulmonary resuscitation before HFNC initiation; 5.Any other condition that the investigator considers unsuitable for enrollment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung Ultrasound;EIT data;Diaphragm ultrasound; | — |
Secondary
| Measure | Time frame |
|---|---|
| Else clinical outcome;High-flow nasal cannula oxygen therapy failure; | — |
Countries
China
Contacts
Public ContactHongping Qu
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed