Gynecological diseases
Conditions
Interventions
alfentanil infusion group:In the pump infusion group, anesthesia was induced 2 minutes prior to surgery with intravenous propofol (2 mg/kg) and alfentanil (5 µg/kg), administered slowly over 30–60 sec
Single-Dose Alfentanil Administration Group :In the single-dose alfentanil group, propofol (2 mg/kg) and alfentanil (10 µg/kg) were administered intravenously over 60 seconds, 2 minutes prior to surg
Sponsors
Maternal and Child Health Hospital of Hubei Province
Eligibility
Sex/Gender
Female
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for hysteroscopy at this institution are anticipated to undergo procedures lasting no longer than 45 minutes. 2. Female patients aged 20–60 years. 3. American Society of Anesthesiologists (ASA) physical status classification I or II. 4. Absence of cardiovascular disease and normal hepatic and renal function, as confirmed by standard laboratory assessments. 5. Participation in this study is voluntary; eligible individuals who have received and comprehended the full informed consent information may indicate their willingness to participate by signing the written informed consent form.
Exclusion criteria
Exclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status classification = III, or presence of severe cardiovascular disease or significantly compromised functional capacity; 2. Current or past psychiatric disorder requiring clinical management; 3. Current or recent use (within the preceding 30 days) of central nervous system–active medications, including antipsychotics, anxiolytics, antidepressants, or benzodiazepines; 4. Pre-procedural systolic blood pressure < 90 mmHg or diastolic blood pressure < 60 mmHg, and/or heart rate < 60 beats per minute measured in the clinical setting; 5. Known hypersensitivity to any study drug or its excipients; 6. History of poor recovery from anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate;Oxygen saturation;blood presure;Degree of satisfaction;intraoperative medication;awakening time;Postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactYingyao Quan
Maternal and Child Health Hospital of Hubei Province
Outcome results
None listed