Breast cancer
Conditions
Interventions
Control group:Manual injection method
Experimental group:Instrument constant-speed injection method
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Female breast cancer patients histologically confirmed as HER2-positive. 2.Have completed at least one subcutaneous injection of Phesgo, with at least three planned injections remaining. 3.No history of acute allergic reactions (e.g., Grade 1-2 allergic reactions) during previous Phesgo injections. 4.Aged between 18 and 70 years (inclusive). 5.No use of pain medications, pain patches, or pain pumps for pain management within 3 days prior to injection. 6.Normal activity level (ECOG score 0-2), no limb paralysis, and able to clearly express personal feelings. 7.Signed informed consent form and voluntarily agreed to participate in this study.
Exclusion criteria
Exclusion criteria: 1.Presence of any skin diseases or conditions affecting subcutaneous injection (e.g., severe infection or dermatitis at the injection site). 2.Simultaneous participation in other clinical trials that may interfere with the results of this study. 3.Cognitive impairment or mental illness preventing completion of study questionnaires and assessments. 4.Regular use of analgesics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Local adverse reactions: induration, itching, subcutaneous hemorrhage, erythema, ecchymosis;Nurse fatigue level;Patient preference;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactPengyanting
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed