Acute lower respiratory tract infection, Mycoplasma pneumoniae pneumonia
Conditions
Interventions
Azithromycin Group:Azithromycin administration
Doxycycline Group:Doxycycline medication
Sponsors
Beijing Childrens Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
8 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Children diagnosed with mycoplasma pneumonia according to the "Diagnosis and Treatment Guidelines for Mycoplasma Pneumonia in Children (2025 Edition)" and the "Expert Clarification on Diagnosis and Treatment of Mycoplasma Pneumonia in Children"; 2. Age >= 8 years old; 3. Duration of illness <= 5 days
Exclusion criteria
Exclusion criteria: 1.Antibiotics such as tetracyclines and quinolones have been administered outside the hospital for treatment; 2.Those who did not respond after 72 hours of treatment with azithromycin should be given further treatment; 3.Those who are allergic to the drugs used in this study; 4.Those with combined immunodeficiency diseases or other underlying diseases such as lung, liver, kidney or heart disorders; 5.Those who have combined infections; 6.Clinical phenotype: critical; 7.Those with poor compliance or the patients and their guardians do not agree to participate in this stud;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of post-treatment pulmonary sequelae on the 90th day;Drug conversion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of days after medication when fever subsides;The number of days for the disappearance of respiratory symptoms and signs;Whether the lung images have completely absorbed and the number of days for absorption;The frequency of bronchoscopy and the characteristics of bronchoscopy under endoscopy;Hospitalization expenses;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactYang Haiming
Beijing Childrens Hospital,Capital Medical University
Outcome results
None listed