Post-stroke postural equilibrium disorder
Conditions
Interventions
Healthy Control Group:NA
VR-TOT group :VR core training assistance system
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patient Cohort: (1) Age: 45-75 years old; (2) Meets the diagnostic criteria of cerebral infarction and cerebral hemorrhage in the "Diagnostic Points of Various Major Cerebrovascular Diseases in China 2019" issued by the Cerebrovascular Epidemiology Group of the Chinese Medical Association Neurology Branch; (3) Single lesion and unilateral disease; (4) The recovery period is between 1 and 3 months; (5) Hemiplegic limb Brunnstrom >= stage 3; (6) Can sit and stand alone; (7) No oral medication that interferes with balance; (8) Blood pressure (drug or non-drug treatment): high =1.04mmol/L, low-density lipoprotein <4.14mmol/L, total cholesterol <6.22mmol/L, triglyceride <2.26mmol/L; (11) Body mass index (BMI) < 28; (12) Blood homocysteine level <15mmol/L; (13) Cardiac function stage (NYHA stage) <= stage I; (14) Volunteer to participate in the study and sign the informed consent. If the subject is unable to read and sign the informed consent due to incapacity or other reasons, the guardian shall act as the agent of the informed process and sign the informed consent. If the subject does not have the ability to read the informed consent (e.g., illiterate subjects), a witness must witness the informed process and sign the informed consent. 2. Healthy Cohort: (1) Healthy individuals undergoing health check-ups at the Physical Examination Center of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine; (2) Deemed generally healthy by the investigator, with medical history, physical examination, vital signs, 12-lead ECG, and laboratory tests within normal ranges or showing only minor abnormalities of no clinical significance; (3) Body mass index (BMI) < 28; (4) Aged 45 to 75 years old; (5) No history of stroke, sensory disorders, severe diabetes, peripheral neuropathy, severe heart/liver/lung/kidney diseases, malignant tumors, mental illnesses, or any other medical history that may interfere with the evaluation; (6) Voluntarily participate in this study and sign the informed consent form. If a participant is unable to read the informed consent form (e.g., illiterate participants), a witness must witness the informed consent process and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Limb movement disorders caused by bone joint and neuromuscular diseases. 2.Complicated with major organs (heart, lung, liver and kidney, etc.) dysfunction, cancer, disease changes at any time. 3.Recently suffered from deep venous thromboembolism of lower extremity. 4.People with other disorders that affect balance, such as cerebellar lesions, visual impairments, vertigo, etc. 5.Vulnerable groups other than the elderly/illiterate, including the mentally ill, the cognitively impaired, the critically ill, pregnant women, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Standing stability test;APAs and CPAs postural adjustment tests;Infrared brain imaging detection;Magnetic resonance imaging detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rehabilitation evaluation;Detection of peripheral blood related factors; | — |
Countries
China
Contacts
Public ContactLijianhua
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed