Atelectasis, postoperative pulmonary complications
Conditions
Interventions
PEEP-5 group:Fix PEEP at 5cmH20
PEEP-EIT group:Dynamic Adaptive PEEP based on EIT
Sponsors
Beijing Huaxin Hospital (The First Affiliated Hospital of Tsinghua University)
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients preparing for laparoscopic radical resection of colon cancer; 2. The patient or his/her family member signs the informed consent form for this trial; 3. Age >= 65 years old; 4. ASA <= grade III; 5. BMI 18 - 30 kg/m^2; 6. The estimated operation time exceeds 2 hours
Exclusion criteria
Exclusion criteria: 1.Subjects without civil capacity; 2.Preoperative SpO2 < 92% when breathing air; 3.Severe respiratory system diseases (including severe COPD, pulmonary fibrosis, pulmonary bullae, etc.), cardiovascular and cerebrovascular diseases (including severe coronary heart disease, heart failure, pulmonary hypertension, aneurysm, etc.), liver and kidney function impairment; 4.Thoracic and spinal deformities, presence of cardiac implants; 5.Participation in other clinical studies within the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of alveolar collapse in the area relied upon during the operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Platform pressure;Driving pressure;Mean arterial pressure;Pulse oxygen saturation;Ventilation center;Oxygenation index;Global inhomogeneity index;Heart rate;Dynamic lung compliance; | — |
Countries
China
Contacts
Public ContactZhu Chengxuan
Beijing Huaxin Hospital (The First Affiliated Hospital of Tsinghua University)
Outcome results
None listed