Cerebral Arteriovenous Malformation
Conditions
Interventions
Observational group:None
Sponsors
Guangdong Second Provincial General Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 65 Years
Inclusion criteria
Inclusion criteria: 1. At least one bAVM confirmed by imaging (CTA/MRA/DSA); 2. bAVM patients aged =65 years, both sexes eligible; 3. Able to cooperate with the researcher in completing study-related procedures and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with comorbidities or an expected life expectancy of less than 10 years; 2. Patients with thrombocytopenia (1.5); 3. Patients diagnosed with bAVM in the context of Moya-Moya-type changes; 4. Patients with any other form of intracranial vascular-related disease, such as spinal arteriovenous fistula, cavernous malformation, dural arteriovenous fistula, developmental venous anomaly, hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber), or phakomatoses/neurocutaneous syndromes such as cerebelloretinal hemangioblastomatosis (von Hippel-Lindau), encephalotrigeminal angiomatosis (Sturge-Weber), or Wyburn-Mason syndrome; 5. Patients currently participating in another study that may affect the outcome assessment of this trial; 6. Other conditions where the investigator considers participation in this trial may pose significant risk to the subject.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical impairment (modified Rankin Scale score >=2) or death at 5-year follow-up; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of permanent neurological deficit (MRS >2) due to perioperative complications lasting more than 3 months;Symptomatic stroke due to any cause;Incidence of any adverse event;Patient functional outcomes (modified Barthel Index, SF-36 questionnaire, NIH Stroke Scale); | — |
Countries
China
Contacts
Public ContactHe Xuying
Guangdong Second Provincial General Hospital
Outcome results
None listed