Lumbar Disc Herniation? (LDH),Lumbar Vertebral Fracture?
Conditions
Interventions
T Group (Tegileridine ):A loading dose of tegileridine 0.75 mg (5 mL) was administered 5 minutes before the end of surgery. The postoperative infusion pump solution was prepared as 0.9% normal saline
S Group (Sufentanil):A loading dose of sufentanil 3 µg was administered 5 minutes before the end of surgery. The postoperative patient-controlled analgesia infusion pump solution was prepared by mixin
Sponsors
The Second Hospital of Lanzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who have undergone posterior lumbar surgery; 2. Age range: 18–65 years; 3. ASA I–II; 4. Agree to participate in the trial and sign the anesthesia informed consent form
Exclusion criteria
Exclusion criteria: 1. History of severe congenital heart disease, liver, or kidney disease; 2. Severe hearing or visual impairment; 3. Mental illness or cognitive impairment; 4. History of alcohol abuse; severe hepatic or renal impairment (Child-Pugh Class C or eGFR 3 months).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS scores at rest and during movement within 48 hours postoperatively.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative recovery time points, including the time to first oral intake, time to first urination, time to first flatus, and time to first ambulation, were recorded.;PCA attempts;Incidence of postoperative nausea, vomiting, and respiratory depression;American Pain Society Pain Outcomes Questionnaire-Revised (APS-POQ-R);Patient recovery quality was assessed using the 15-item Quality of Recovery (QoR-15) questionnaire at 24 hours, 48 hours, and 1 week postoperatively.; | — |
Countries
China
Contacts
Public ContactYiHan Wang
The Second Hospital of Lanzhou University
Outcome results
None listed