Potential malignant lesion of the oral mucosa
Conditions
Interventions
Gold Standard:Histopathological examination of biopsy specimens will serve as the gold/reference standard. All enrolled cases will undergo biopsy, and pathological grading will be determined according
Index test:The index tests are noninvasive oral exfoliative cell-based assessments, including liquid-based cytology (LBC), DNA ploidy analysis, and DNA methylation testing (ZNF582 and SHOX2), and a tr
Sponsors
Hospital of Stomatology, SunYat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Clinical and pathological diagnosis of oral erythema, oral leukoplakia, oral lichen planus, oral submucosal fibrosis, and other potential malignant lesions in the oral cavity with mild, moderate, and severe abnormal hyperplasia of mucosal epithelium, as well as patients with squamous cell carcinoma; 2.Not treated with hormones, lasers, radiation, or chemical drugs; 3.People who can sign informed consent forms;
Exclusion criteria
Exclusion criteria: 1.Unable to meet follow-up requirements; 2.Massive missing or incomplete data;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The model's ability to distinguish; | — |
Secondary
| Measure | Time frame |
|---|---|
| The consistency and calibration performance of the prediction model; | — |
Countries
China
Contacts
Public ContactJuan Xia
Hospital of Stomatology, SunYat-sen University
Outcome results
None listed