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A study on the Value of Lactic Acid and Lactic Acid Modification in Neonatal Hypoxic-Ischemic Encephalopathy

A study on the Value of Lactic Acid and Lactic Acid Modification in Neonatal Hypoxic-Ischemic Encephalopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122256
Enrollment
Unknown
Registered
2026-04-10
Start date
2026-04-12
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal hypoxic-ischemic encephalopathy

Interventions

neonatal hypoxic-ischemic encephalopathy:None
Control group:None

Sponsors

The affiliated hospital of southwest medical university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 28 Days

Inclusion criteria

Inclusion criteria: Case group: 1. Meets the diagnostic criteria for HIE; 2. Has complete clinical data. Control group: 1. Gestational age at birth >= 35 weeks; 2. Apgar score >= 8 at 1 minute, >= 9 at 5 minutes; 3. No history of asphyxia, no neurological disorders or other serious diseases.

Exclusion criteria

Exclusion criteria: 1. Exclude other diseases that may cause neurological abnormalities in newborns, such as genetic metabolic disorders, congenital central nervous system malformations, electrolyte imbalances, and birth injuries, etc. 2. The clinical data is incomplete.

Design outcomes

Primary

MeasureTime frame
The level of lysine 18 lactylation (H3K18la) of histone H3;—

Countries

China

Contacts

Public ContactDong Wenbin

The affiliated hospital of southwest medical university

dongwenbin2000@163.com+86 13518389718

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026