Coronary heart disease
Conditions
Interventions
Group A:Energy-Restricted Low-Fat Diet
Group B:Low-Carbohydrate High-Protein Diet
Group C:Cantonese Balanced Diet
Sponsors
Guangdong Provincial People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Participants must meet all of the following criteria: 1. Age between 18 and 70 years. 2. Body mass index (BMI) >= 24 kg/m² and increased waist circumference (>= 90 cm for men or >= 85 cm for women). 3. Chronic stable coronary heart disease, defined as a history of myocardial infarction (>= 1 month prior to randomization), prior percutaneous coronary intervention, prior coronary artery bypass grafting (CABG), or angiographically confirmed multivessel coronary artery disease. 4. Willingness to lose weight through lifestyle interventions. 5. Residence in Guangdong Province with no plans to relocate or travel outside the province during the next year. 6. Ability and willingness to provide written informed consent.
Exclusion criteria
Exclusion criteria: Participants meeting any of the following criteria will be excluded: 1. Diagnosis of type 1 diabetes mellitus. 2. Left ventricular systolic dysfunction with left ventricular ejection fraction (LVEF) 120 U/L or ALT > 150 U/L); or self-reported history of chronic hepatitis B with positivity for hepatitis B surface antigen [HBsAg], hepatitis B e antigen [HBeAg], and hepatitis B core antibody [anti-HBc]; or active viral hepatitis. 6. Severe renal impairment (estimated glomerular filtration rate [eGFR] =5 kg within the past 3 months. 20. Unwillingness or inability to modify habitual dietary patterns, or presence of special dietary requirements (e.g., vegetarian diet). 21. A hous
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight;BMI;waist circumference;Waist-to-hip ratio;Waist-to-height ratio; | — |
Countries
China
Contacts
Public ContactHe Xuyu
Guangdong Provincial People’s Hospital
Outcome results
None listed