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Effect of Repetitive Transcranial Magnetic Stimulation on the Unaffected Side on Upper Limb Motor Function in Severe Stroke and the Study of Neuroplasticity Mechanisms

Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on the Unaffected Side on Upper Limb Motor Function in Severe Stroke and the Study of Neuroplasticity Mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122250
Enrollment
Unknown
Registered
2026-04-10
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Stroke diagnosis consistent with the diagnostic and treatment guidelines for intracerebral hemorrhage or acute ischemic stroke in China established by the Neurology Branch of the Chinese Medical Association, and confirmed by imaging examinations such as cranial CT or cranial MRI; 2. First-time, unilateral onset, with disease duration ranging from 2 weeks to 3 months; 3. Age between 30 and 85 years; 4. Presence of severe unilateral upper limb motor dysfunction, Brunnstrom stage < 3, and Fugl-Meyer Upper Extremity Motor Function Score < 22/66; 5. Written informed consent provided by the participant or their legal representative.

Exclusion criteria

Exclusion criteria: 1. History of epileptic seizures; 2. Severe systemic injury or accompanied by other serious illnesses; 3. Severe aphasia or cognitive impairment, unable to cooperate and complete the study; 4. Presence of any contraindications for transcranial magnetic stimulation (such as intracranial metal implants or cardiac pacemakers); 5. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer assessment of the upper extremity;Brain function;

Secondary

MeasureTime frame
Neurophysiological MEPs;

Countries

China

Contacts

Public ContactChunfeng Xia

Weifang People's Hospital

xcf198828@163.com+86 536 819 2677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026