Congenital Cataract or Developmental Cataract
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children with Congenital Cataracts 1. Age between 0 and 30 years; 2. History of bilateral congenital/developmental cataracts; 3. Underwent bilateral cataract extraction with intraocular lens implantation before the age of 8; 4. Regular use of corrective lenses postoperatively; 5. For minors, informed consent signed by parents or legal guardians. Normal Subjects 1. Age between 0 and 30 years; 2. For minors, informed consent signed by parents or legal guardians.
Exclusion criteria
Exclusion criteria: 1. Premature birth (<28 weeks); 2. Presence of eye diseases other than refractive errors (cataract, keratitis, corneal leukoma, aniridia, glaucoma, amblyopia) or systemic diseases (congenital heart disease, ischemic encephalopathy); 3. Family history of eye diseases (any congenital eye disease, such as congenital glaucoma, congenital aniridia); 4. History of ocular trauma; 5. Severe ocular comorbidities (small cornea, persistent hyperplastic primary vitreous, rubella, Lowe syndrome); 6. Difficulties in cooperating with examinations; 7. Currently participating in other clinical trials; 8. Considered by the investigator as unsuitable for this clinical trial for other reasons; 9. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Task?Based fMRI Activation Intensity/Extent;Contrast Sensitivity; | — |
Countries
China
Contacts
Zhongshan Ophthalmic Center,Sun Yat-sen University