Renal Calculi
Conditions
Interventions
Intervention group:Percutaneous nephrolithotomy (PCNL) guided by renal pelvis contrast-enhanced ultrasonography
Control group:PCNL guided by conventional ultrasonography.
Sponsors
The First Medical Center of the Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Diagnosis of renal calculi confirmed by abdominal radiography (KUB), ultrasonography,or urological CT, with stone diameter >= 2 cm, multiple renal calculi, or staghorn calculi; 3. The target renal calyx is non-dilated, or mild hydronephrosis is diagnosed (manifested on ultrasound as normal renal parenchymal thickness and echogenicity, normal renal volume, separation of the collecting system by 1.5-3 cm, with O-shaped or C-shaped anechoic areas visible within the renal sinus); 4. Provision of signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative or intraoperative evidence of hydronephrosis. 2. Presence of unmanageable urinary tract infection, sepsis, or pyelonephritis. 3. Complex calculi requiring multi-tract access. 4. Bilateral proximal ureteral or bilateral renal calculi. 5. History of previous ipsilateral PCNL. 6. Calculi associated with anatomical anomalies (e.g., calculi in solitary kidney, duplex kidney, duplex renal pelvis, horseshoe kidney, or medullary sponge kidney). 7. Coexistent renal tumor. 8. Patients deemed unfit for surgery due to significant cardiac, cerebral, pulmonary, or other comorbidities. 9. Patients unable to maintain the prone position due to severe spinal deformity or obesity. 10. Contraindications to ultrasound contrast agents (e.g., right-to-left cardiac shunts, known hypersensitivity to contrast agents). 11. Pregnant or lactating women. 12. Concurrent participation in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The first puncture success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Puncture time;Channel establishment time;Postoperative hospital stay;time of operation;Residual stone rate; | — |
Countries
China
Contacts
Public ContactMai Haixing
The First Medical Center of the Chinese PLA General Hospital
Outcome results
None listed