Gout combined with CKD
Conditions
Interventions
uric acid-lowering compound granules:None
standard protocol in the guidelines:None
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age between 18 and 75 years. (2) Diagnosed with gout based on clinical symptoms (such as joint pain, redness and swelling), serum uric acid levels (male serum uric acid > 420 µmol/L, female serum uric acid > 360 µmol/L), and joint imaging examination. (3) Estimated glomerular filtration rate (eGFR) indicating CKD stages 2-4 (15 < eGFR = 75 ml/min·1.73m²). (4) Patient has signed the informed consent form, voluntarily participates in the study, and is able to cooperate with follow-up.
Exclusion criteria
Exclusion criteria: (1) Combine other chronic diseases that seriously affect research results, such as advanced malignant tumors, severe cardiopulmonary failure, etc. (2) Use of special drugs that may affect gout or kidney function within the past 3 months (such as unapproved experimental drugs, high-dose corticosteroid pulse therapy, etc.). (3) Presence of mental illness or cognitive impairment, unable to cooperate with the study. (4) Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glomerular Filtration Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Uric-Acid;Blood Creatinine;Blood Urea Nitrogen;Blood lipids;24-hour Urinary Total Protein;24h urinary uric acid;Urinary Albumin-to-Creatinine Ratio;Gout ; | — |
Countries
China
Contacts
Public ContactGao Jiandong
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed