Osteoarthritis, Total Knee Arthroplasty
Conditions
Interventions
treatment group:Bone surface + prosthesis surface covered with bone cement
control group:Bone surface covered with bone cement only
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 50–75 years, unilateral primary TKA, primary knee osteoarthritis (Kellgren-Lawrence Grade III–IV); 2. Adequate bone stock at distal femur/proximal tibia (bone mineral density T-score >= -2.5), no bone defects (<=2mm); 3. No cement allergy or coagulation disorders; able to complete follow-up visits and MAR-CT scans; 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Revision TKA, bilateral simultaneous TKA, or combined with other joint surgeries; 2. Preoperative knee deformity (valgus/varus >15°) or ligament insufficiency requiring a restrictive prosthesis; 3. History of prior knee surgery, osteomyelitis, or infectious arthritis; 4. Psychiatric disorders, cognitive impairment, or inability to cooperate with 3D quantitative analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone Cement Penetration Depth;Percentage of interface contact area;Interface gap width and distribution uniformity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Actual intraoperative bone cement usage;Operative duration and incidence of postoperative adverse events (infection, bleeding, deep vein thrombosis, etc.);Postoperative clinical functional recovery; | — |
Countries
China
Contacts
Public ContactZeng Yi
West China Hospital, Sichuan University
Outcome results
None listed