pathological scar
Conditions
Interventions
Wendesilin Hyaluronic Acid Hydrogel Treatment Group:Local application of Wendesilin sodium hyaluronate hydrogel bio-glue
Sponsors
Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 14 to 65 years (including 14 years, but excluding 65 years), and in good health. 2. Patients who undergo the following surgical treatments in our hospital and meet the corresponding criteria: A. pathological scar excision surgery (scar length =4 cm); B. split-thickness skin graft donor site (donor area >20 cm²). 3. Patients with complete preoperative data, mainly including standard preoperative photographs, demographic data, and disease-related data. 4. Patients who have read and signed the informed consent form before the start of the study.
Exclusion criteria
Exclusion criteria: 1. Patients who are unable to complete effective follow-up due to various reasons. 2. Patients who receive additional interventions during the postoperative follow-up period that may affect scar healing outcomes, including reoperation other than that required for the management of complications; radiotherapy; local intralesional scar injection therapy; and other interventions that may significantly affect scar formation. 3. Patients with pre-existing arteriovenous disease, neoplastic disease, excessively large pathological scars, or scars crossing joints. 4. Patients with a previous definite diagnosis of keloid or with typical clinical manifestations of keloid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of pathological scars within 12 months postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Scar Assessment Scale (PSAS) score;Observer Scar Assessment Scale (OSAS) score; | — |
Countries
China
Contacts
Public ContactPeiru Min
Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital
Outcome results
None listed