alcohol use disorder
Conditions
Interventions
True stimulus group:intermittent Theta Burst Stimulation
pseudo-stimulus group:intermittent Theta Burst Stimulation
Sponsors
Hebei Provincial Mental Health Center
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Males aged between 18 and 60 years; 2. Meet the moderate to severe diagnostic criteria for Alcohol Use Disorder according to DSM-5; 3. Alcohol Withdrawal Assessment (CIWA-Ar) = 9 points; 4. Cognitive screening using the Montreal Cognitive Assessment (MoCA) (score greater than 21 points); 5. Normal or corrected-to-normal vision, able to complete computerized cognitive tasks; 6. Written informed consent obtained from the individual or their guardian; 7. Right-handed.
Exclusion criteria
Exclusion criteria: 1. Alcohol withdrawal assessment scale (CIWA-Ar) > 9 points 2. History of head disease, brain injury, epileptic seizures, or other neurological disorders, as well as severe systemic diseases such as cardiovascular, respiratory, or immune system disorders; 3. Mental or neurological disorders caused by other factors, or coexisting with other psychiatric diagnoses; 4. Significant sensory-motor impairments that prevent the use of a computer; 5. Presence of contraindications for iTBS, such as metallic implants in the brain; 6. Women who are pregnant or breastfeeding; 7. Severe cognitive impairment; 8. Dependence on other psychoactive substances (excluding nicotine); 9. Severe psychotic symptoms or a high risk of suicide; 10. Inability to remain basically still during the examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Barratt Impulsiveness Scale, Version 11;Event-related potential P300;Event-related potential N200;Behavioral indicators of the GO/NO-GO experimental paradigm; | — |
Countries
China
Contacts
Public ContactZhang Jiawei
Hebei Provincial Mental Health Center
Outcome results
None listed