Cervical Spondylotic Myelopathy, CSM
Conditions
Interventions
CSM Patient Group:None
Healthy Control Group:None
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Age
No minimum to 65 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in this study; 2. Present clinical symptoms or signs of cervical spinal cord damage; 3. Cervical MRI confirms significant compression of the spinal cord, including intervertebral disc protrusion and posterior longitudinal ligament ossification; 4. Without undergoing decompression surgery or drug treatment; 5. Without amyotrophic lateral sclerosis of the spinal cord, spinal cord tumors, secondary adhesive arachnoiditis, spinal cord injury, multiple peripheral neuritis, etc. 6. Right-handed.
Exclusion criteria
Exclusion criteria: 1. Age > 65 years old; 2. History of other neurological diseases; 3. History of mental illness; 4. Patients with poor cooperation and significant head movement during scanning, resulting in poor image quality; 5. History of brain or cervical spine surgery; 6. Claustrophobia and other conditions unsuitable for magnetic resonance scanning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensory-Motor Gradient (Sensory-Motor Network Gradient Slope / Structural-Functional Coupling Strength SFT Continuum); | — |
Secondary
| Measure | Time frame |
|---|---|
| Network Compensation-Related Metrics (Key Network Topological Properties: Global Efficiency, Node Centrality);Brain Structural Metrics (High-Resolution Structural MRI Quantification of Spinal Cord Compression Severity and Morphological Changes: Cross-Sectional Area CSA, Atrophy Volume);Spinal White Matter Tract Microstructural Injury Metrics (Fractional Anisotropy FA, Mean Diffusivity MD);Cognitive Function Metrics (Montreal Cognitive Assessment Total Score and Domain-Specific Scores); | — |
Countries
China
Contacts
Public ContactTan Yongming
The first affiliated hostipal of nanchang university
Outcome results
None listed