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Lactylation of HADHA and its Association with Cardiac Function and Clinical Outcomes in Patients with Sepsis-Induced Cardiomyopathy: A Prospective Cohort Study

Lactylation of HADHA and its Association with Cardiac Function and Clinical Outcomes in Patients with Sepsis-Induced Cardiomyopathy: A Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122203
Enrollment
Unknown
Registered
2026-04-10
Start date
2026-04-10
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis-Induced Cardiomyopathy

Interventions

Sepsis-induced cardiomyopathy observation group:None

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. Patients who have been clinically evaluated and meet the diagnostic criteria for sepsis and septic cardiomyopathy; 3. ICU hospitalization time >= 24 hours; 4. Agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Previous diagnosis of heart failure, chronic hepatic or renal failure, autoimmune disease, or malignancy; 2.Age <18 years; 3.Pregnant women; 4.Patients with an anticipated survival period of less than 24 hours or those who are unable to complete the follow-up process.

Design outcomes

Primary

MeasureTime frame
90-day mortality rate;—

Secondary

MeasureTime frame
Cardiac function;—

Countries

China

Contacts

Public ContactYiyue Zhong

Affiliated Hospital of Guangdong Medical University

zyy0803@126.com+86 759 2387546

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026